The hearing is the first of three for Obama's national security nominees, and the least controversial.
Hagel will face tough questions about his past statements on Israel, Iran, nuclear weapons and defense spending at his confirmation hearing next Thursday before the Senate Armed Services Committee. John Brennan, the president's choice for CIA director, will be quizzed about White House national security leaks and the use of unmanned drones at his hearing next month.
The job of the nation's top diplomat would be the realization of a dream for Kerry, whom Obama passed over in 2008 when he chose Clinton. When Joe Biden became vice president, Kerry replaced the former Delaware senator as chairman of the committee.
Obama nominated Kerry after Susan Rice, the U.S. ambassador to the United Nations, removed her name from consideration following criticism from Republicans over her initial comments about the attacks on the U.S. Consulate in Benghazi, Libya.
Kerry, 69, is the son of a diplomat and has served as Obama's unofficial envoy, using his skills of persuasion with leaders of Afghanistan and Pakistan.
In advance of the hearing, Kerry said he plans to divest holdings in dozens of companies in his family's vast financial portfolio to avoid conflicts of interest if he is confirmed.
He notified the State Department earlier this month that within 90 days of his confirmation he would move to sell off holdings in three trusts benefiting him and his wife, Teresa Heinz Kerry. In the Jan. 8 letter to the department's Office of the Legal Adviser, Kerry said he would not take part in any decisions that could affect the companies he has holdings in until those investments are sold off.
Kerry is the wealthiest man in the Senate, worth more than $184 million, according to a 2011 Senate disclosure.